Meta Analysis Clinical

Catalog

• Conduct meta-analysis of 20 RCTs on statin effectiveness for primary prevention. Help me: 1) Extract outcomes (mortality, cardiovascular events) from each trial, 2) Calculate pooled odds ratios and risk differences, 3) Assess heterogeneity (I², τ², Q test), 4) Perform sensitivity analyses, 5) Test for publication bias (funnel plot, Egger test, trim-and-fill), 6) Conduct subgroup analyses by patient characteristics, 7) Assess quality of evidence using GRADE