I need to make my meta-analysis transparent and open. Help me: 1) Preregister meta-analysis protocol (PROSPERO)

Prompt
I need to make my meta-analysis transparent and open. Help me: 1) Preregister meta-analysis protocol (PROSPERO)
ChatGPTOpenAI
I need to make my meta-analysis transparent and open. Help me: 1) Preregister meta-analysis protocol (PROSPERO)

Preregistering your meta-analysis protocol in a database like PROSPERO (International Prospective Register of Systematic Reviews) is a great step towards transparency and openness in research. Here’s how you can go about it:

Steps to Preregister a Meta-Analysis Protocol on PROSPERO:


  • Visit the PROSPERO Website:

Go to the official PROSPERO website: https://www.crd.york.ac.uk/prospero/.
  • Register for an Account:

If you haven’t already, you will need to create an account. Look for the “Register” or “Sign Up” option on the homepage.
  • Read the Guidance Notes:

Before you start filling out the registration form, review the guidance notes provided by PROSPERO to ensure you meet the requirements for registration and understand what information is needed for your protocol.
  • Prepare Your Meta-Analysis Protocol:

Make sure to compile the key components of your meta-analysis protocol, which typically includes:
  • Title: A concise title describing your meta-analysis.

  • Review Question: The specific question your meta-analysis will address.

  • Objectives: Define the main objectives of the meta-analysis.

  • Eligibility Criteria: Specify the inclusion and exclusion criteria for studies.

  • Information Sources: List the databases and other sources you will search.

  • Data Extraction: Describe how you will extract and manage data from the included studies.

  • Risk of Bias Assessment: Explain how you will assess the risk of bias in the included studies.

  • Statistical Analysis: Outline your planned statistical methods and analyses.

  • Funding and Conflicts of Interest: Disclose any funding sources and potential conflicts of interest.

  • Complete the Registration Form:

Use the information you prepared to fill out the registration form on the PROSPERO website. Make sure to provide as much detail as possible, as this will enhance the transparency of your protocol.
  • Review Your Submission:

Before submitting, review all the entries to ensure accuracy and completeness.
  • Submit the Protocol:

After ensuring everything is accurate, submit your protocol for registration.
  • Receive Your PROSPERO Registration Number:

Once approved, you will receive a unique PROSPERO registration number. This number can be cited in your publications and presentations to denote that your meta-analysis protocol is registered.

Additional Tips:


  • Be Clear and Precise: Clarity in your registration fosters transparency, allowing others to understand your methods and objectives easily.

  • Update if Necessary: If you make significant changes to your protocol after registering, you should update your registration on PROSPERO accordingly.

  • Follow Reporting Standards: Consider following established reporting standards for systematic reviews and meta-analyses, such as PRISMA, when preparing your protocol and reporting your findings.


By following these steps, you will provide a transparent overview of your planned meta-analysis, contributing to the integrity of research in your field. Good luck with your meta-analysis!

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MistralMistral AI
I need to make my meta-analysis transparent and open. Help me: 1) Preregister meta-analysis protocol (PROSPERO)

Preregistering your meta-analysis protocol is a crucial step in ensuring transparency and openness in your research. PROSPERO (International Prospective Register of Systematic Reviews) is a widely recognized platform for registering systematic reviews and meta-analyses. Here’s a step-by-step guide to help you preregister your meta-analysis protocol on PROSPERO:

Step 1: Prepare Your Protocol


Before you register, you need to have a well-prepared protocol. This should include:
  • Title: A clear and concise title that describes the focus of your meta-analysis.

  • Objectives: Specific research questions or hypotheses you aim to address.

  • Eligibility Criteria: Inclusion and exclusion criteria for studies.

  • Information Sources: Databases and other sources you will search.

  • Search Strategy: Detailed search terms and strategies.

  • Study Selection: Methods for selecting studies, including screening and eligibility assessment.

  • Data Collection Process: Methods for data extraction and management.

  • Data Items: Specific data items you will collect from each study.

  • Risk of Bias Assessment: Methods for assessing the risk of bias in individual studies.

  • Synthesis of Results: Methods for synthesizing the data, including statistical methods.

  • Additional Analyses: Plans for additional analyses, such as subgroup analyses or sensitivity analyses.

  • Timeline: Estimated timeline for completing the meta-analysis.


Step 2: Create an Account on PROSPERO


  • Go to the PROSPERO website.

  • Click on "Register" to create a new account.

  • Fill in the required information and submit your registration.


Step 3: Register Your Protocol


  • Log in to your PROSPERO account.

  • Click on "Register a new review."

  • Fill in the required fields based on your prepared protocol. Key sections include:

  • Title and Abstract: Provide a brief summary of your meta-analysis.

  • Review Team: List the names and affiliations of all team members.

  • Review Methods: Detail your methods, including eligibility criteria, information sources, search strategy, study selection, data collection process, data items, risk of bias assessment, synthesis of results, and additional analyses.

  • Timeline: Provide an estimated timeline for completing the review.

  • Review all the information you have entered to ensure accuracy and completeness.

  • Submit your protocol for review.


Step 4: Review and Approval


  • Your protocol will be reviewed by the PROSPERO editorial team.

  • You may receive feedback or requests for clarification. Address these promptly.

  • Once approved, your protocol will be assigned a unique registration number and will be publicly available on the PROSPERO website.


Step 5: Update and Amendments


  • If you need to make any changes to your protocol after registration, you can submit amendments through the PROSPERO system.

  • Keep your protocol updated with any significant changes or deviations from the original plan.


Additional Tips


  • Transparency: Be as transparent as possible in your protocol. Provide detailed information to ensure reproducibility.

  • Open Access: Consider making your protocol and any subsequent publications open access to maximize transparency and impact.

  • Reporting Standards: Follow reporting standards such as PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) to ensure high-quality reporting.


By following these steps, you can successfully preregister your meta-analysis protocol on PROSPERO, enhancing the transparency and credibility of your research.

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Analysis

This comparison demonstrates the different approaches each AI model takes when responding to the same prompt. Here are the key differences observed:

Response Characteristics

ChatGPT: Provides a direct response with 41 sentences.

Mistral: Provides a direct response with 67 sentences.

Key Takeaways

  • Each model brings unique strengths to this type of query
  • Response styles vary significantly between models
  • Consider your specific use case when choosing between these models

Try This Comparison Yourself

Want to test these models with your own prompts? Visit SNEOS.com to compare AI responses side-by-side in real-time.


This comparison was generated using the SNEOS AI Comparison ToolPublished: October 15, 2025 | Models: ChatGPT, Mistral